Our projects

Dr Tanya Applegate

2.

Scale-up of point-of-care testing strategies to enhance hepatitis C treatment among people who inject drugs: Modelling, affordability and cost-effectiveness analysis.

Status

Completed

Year

2020

 

Named PI/Co-PI

Jason Grebley, Sophy Shih, Richard Gray, Virginia Wiseman

Other investigators

A. Kwon, P. Vickerman, N. Martin

Lead EMCR

Amy Kwon

# of EMCRs

1

Regional setting

Australia

Discipline

Health Economics, Modelling

The Problem

Timely diagnosis and treatment of hepatitis C virus (HCV) is critical to achieve elimination goals. However, conventional lab-based testing for HCV requires multiple visits to health facilities that contributes to low treatment uptake in key populations.

The Solution

Cost-effectiveness analyses were undertaken from the perspective of Australian Governments as funders by modelling point-of-care testing strategies compared to standard-of-care in needle and syringe programs, drug treatment clinics, and prisons. The modelling results suggest testing strategies combining point-of-care HCV antibody and RNA testing has potential to optimise health outcomes and improve efficiency.

Related Publications

b

Optimizing point-of-care testing strategies for diagnosis and treatment of hepatitis C virus infection in Australia: a model-based cost-effectiveness analysis.

Lancet Reg Health West Pac. 2023

Shih STF, Cheng Q, Carson J, Valerio H, Sheehan Y, Gray RT, Cunningham EB, Kwon JA, Lloyd AR, Dore GJ, Wiseman V, Grebely J. More info