Our projects

Dr Tanya Applegate

11.

Effectiveness, cost-effectiveness, barriers and facilitators and implementation strategies for point-of-care testing for HIV, viral hepatitis and STIs: a series of systematic reviews.

Status

Underway

Year

2023

 

Named PI/Co-PI

Guillaume Fontaine, Jason Grebely

Other investigators

E B. Cunningham, B. Hajarizadeh, R. Guy, L. Causer, L. Lafferty, A. Marshall, W. Nichols, S. Mortazhejri, JHC. Hung, B. Hengel, S. Matthews, C. Treloar, T. Applegate, J. Presseau, V. Wiseman, S. Shih, J M. Grimshaw, N. Taylor, L. Wolfenden, M. Kingsland, A. Vallely

Lead EMCR

Guillaume Fontaine

# of EMCRs

10

Regional setting

Global

Discipline

Social Science, Health Economics, Other

The Problem

Point-of-care testing (POCT) for HIV, viral hepatitis, and sexually transmitted infections (STIs) has the potential to improve access to timely diagnosis and care, but its effectiveness, cost-effectiveness, implementation barriers, and facilitators, as well as suitable implementation strategies, remain underexplored. This lack of comprehensive evidence limits the ability to scale up POCT and optimize its impact in diverse healthcare settings.

The Solution

This project involves a series of four systematic reviews addressing key aspects of POCT for HIV, viral hepatitis, and STIs: 1) its clinical effectiveness, 2) its cost-effectiveness, 3) barriers and facilitators to its adoption, and 4) implementation strategies to enhance its integration into healthcare systems. By synthesizing evidence across these domains, the project aims to inform decision-making and support the effective scale-up of POCT. The first review, focusing on clinical effectiveness, is underway with data extraction in progress. A dedicated PhD student will lead reviews on barriers, facilitators, and implementation strategies to ensure focused and thorough analysis.